Mass Spectrometry Quiz

1.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?
- 1868
- 1968
- 1989
Your answer:

Correct answer:

The solution of differential equations of this type came from the French mathematician Émile Léonard Mathieu (1835-1890), who studied the mechanical vibrations of the elliptical drumheads.
2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]
3.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?
- 5
- 7
- 9
Your answer:

Correct answer:

A penta-quadrupole mass spectrometer contains three quadrupole filters and two rf-only quadrupole collision cells. It allows MS³ experiments. Extrel once offered such a spectrometer.
4.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?
- Slovakia
- Czechia
- Poland
Your answer:

Correct answer:

The parents of John Zelený, Antonín Zelený and Josefa Pitková, came from Křídla, a small village near Žďár nad Sázavou in Austria-Hungary (now the Czech Republic).
5.
Who made molecular elephants fly?
- John B. Fenn
- Joseph J. Thomson
- W. and O. Wright
Your answer:

Correct answer:

John Fenn was awarded Nobel Prize in Chemistry in 2002 for his work related to electrospray ionization of biological macromolecules. His famous phrase, "we made elephants fly" refers to the ability of electrospray to generate gas-phase ions from big protein molecules.
6.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:
- Gold
- Iridium
- Rhenium
Your answer:

Correct answer:

The International Prototype of the Kilogram was a cylinder with a height and diameter of 39 mm made of an alloy of 90% platinum and 10% iridium.
7.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?
- Burnaby Munson and Frank H. Field
- Michael Barber
- Hans-Dieter Beckey
Your answer:

Correct answer:

Chemical ionization was discovered in the laboratories of the Humble Oil and Refining Company in Baytown, TX. Munson and Field’s seminal paper on chemical ionization was published in 1966. [https://doi.org/10.1021/ja00964a001]
8.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

Viking 1 carried two mass spectrometers, both equipped with double-focusing analyzers and electron ionization sources. The first spectrometer with a Mattauch-Herzog geometry was designed by Alfred Nier; it was intended to analyze the upper atmosphere of Mars. The second one with a Nier- Johnson geometry was part of the GC/MS apparatus designed by Klaus Biemann. It was used to analyze the regolith and the atmosphere at the landing site.
9.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?
- Francis William Aston
- Wolfgang Paul
- John Bennett Fenn
Your answer:

Correct answer:

Aston is a 44-kilometer lunar impact crater located along the northwestern limb of the Moon. The crater was named in honor of Francis W. Aston.
10.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

4.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

5.
Who made molecular elephants fly?

6.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

7.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

8.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

9.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

10.
What is the electric charge of an ion with m/z = m?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

2. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3. What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

4. John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

5. Who made molecular elephants fly?

6. Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

7. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

8. Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

9. Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

10. What is the electric charge of an ion with m/z = m?

Czech Museumof Mass Spectrometry

Our partners

1.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

4.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

5.
Who made molecular elephants fly?

6.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

7.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

8.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

9.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

10.
What is the electric charge of an ion with m/z = m?

Czech Museum
of Mass Spectrometry