Mass Spectrometry Quiz

1.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?
- Slovakia
- Czechia
- Poland
Your answer:

Correct answer:

The parents of John Zelený, Antonín Zelený and Josefa Pitková, came from Křídla, a small village near Žďár nad Sázavou in Austria-Hungary (now the Czech Republic).
2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]
3.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

Viking 1 carried two mass spectrometers, both equipped with double-focusing analyzers and electron ionization sources. The first spectrometer with a Mattauch-Herzog geometry was designed by Alfred Nier; it was intended to analyze the upper atmosphere of Mars. The second one with a Nier- Johnson geometry was part of the GC/MS apparatus designed by Klaus Biemann. It was used to analyze the regolith and the atmosphere at the landing site.
4.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?
- 5
- 7
- 9
Your answer:

Correct answer:

A penta-quadrupole mass spectrometer contains three quadrupole filters and two rf-only quadrupole collision cells. It allows MS³ experiments. Extrel once offered such a spectrometer.
5.
Which element has the largest number of stable isotopes?
- Molybdenum
- Tin
- Ytterbium
Your answer:

Correct answer:

Naturally occurring tin is a mixture of its ten stable isotopes and they are found in the percentages as follows: ¹¹²Sn (1.0 %), ¹¹⁴Sn (0.7 %), ¹¹⁵Sn (0.3 %), ¹¹⁶Sn (14.5 %), ¹¹⁷Sn (7.7 %), ¹¹⁸Sn (24.2 %), ¹¹⁹Sn (8.6 %), ¹²⁰Sn (32.6 %), ¹²²Sn (4.6 %), and ¹²⁴Sn (5.8 %). Molybdenum has six stable isotopes, ytterbium seven.
6.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- Neither the trajectory nor the velocity of the particle changes
- The particle either accelerates or decelerates, depending on the field direction and the particle charge sign
Your answer:

Correct answer:

If a positive charge is moving in the same direction as the electric field vector the particle's velocity will increase. If it is moving in the opposite direction it will decelerate. If a negative charge is moving in the same direction as the electric field vector the particle will decelerate. If it is moving in the opposite direction it will accelerate.
7.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?
- Berlin, Germany
- Ostrava, Czechia
- Klosterneuburg, Austria
Your answer:

Correct answer:

Josef Mattauch was born in 1895 in the city of Mährisch Ostrau, in what is now the Czech Republic, then part of the Austrian-Hungarian Empire.
8.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?
- 1868
- 1968
- 1989
Your answer:

Correct answer:

The solution of differential equations of this type came from the French mathematician Émile Léonard Mathieu (1835-1890), who studied the mechanical vibrations of the elliptical drumheads.
9.
List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).
- Hydrazine, oxygen, methanol
- Methanol, hydrazine, oxygen
- Oxygen, methanol, hydrazine
Your answer:

Correct answer:

The monoisotopic masses of these compounds are 31.989829 Da (oxygen), 32.026215 Da (methanol), and 32.037448 Da (hydrazine).
10.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

4.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

5.
Which element has the largest number of stable isotopes?

6.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

7.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

8.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

9.
List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).

10.
What is the electric charge of an ion with m/z = m?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

2. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3. Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

4. What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

5. Which element has the largest number of stable isotopes?

6. What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

7. Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

8. The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

9. List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).

10. What is the electric charge of an ion with m/z = m?

Czech Museumof Mass Spectrometry

Our partners

1.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

2.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

3.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

4.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

5.
Which element has the largest number of stable isotopes?

6.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

7.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

8.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

9.
List these compounds according to their increasing mass: hydrazine (H4N2), oxygen (O2), methanol (CH4O).

10.
What is the electric charge of an ion with m/z = m?

Czech Museum
of Mass Spectrometry