Mass Spectrometry Quiz

1.
What principle of positive ray detection was used in the first Thomson's parabola spectrographs?
- Phosphorescence of willemite
- Darkening of a photographic plate
- Charge detection using an electrometer
Your answer:

Correct answer:

In the spectrographs used by Thomson until 1910, the rays of positive electricity were detected by the phosphorescence they produced on a willemite screen. The screen was made by grinding rare zinc mineral willemite into a fine powder. After shaking in alcohol, the suspension was allowed to deposit slowly on a glass plate. Later, a photographic plate inside the spectrograph was used for more sensitive detection.
2.
Which element has the largest number of stable isotopes?
- Molybdenum
- Tin
- Ytterbium
Your answer:

Correct answer:

Naturally occurring tin is a mixture of its ten stable isotopes and they are found in the percentages as follows: ¹¹²Sn (1.0 %), ¹¹⁴Sn (0.7 %), ¹¹⁵Sn (0.3 %), ¹¹⁶Sn (14.5 %), ¹¹⁷Sn (7.7 %), ¹¹⁸Sn (24.2 %), ¹¹⁹Sn (8.6 %), ¹²⁰Sn (32.6 %), ¹²²Sn (4.6 %), and ¹²⁴Sn (5.8 %). Molybdenum has six stable isotopes, ytterbium seven.
3.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:
- Gold
- Iridium
- Rhenium
Your answer:

Correct answer:

The International Prototype of the Kilogram was a cylinder with a height and diameter of 39 mm made of an alloy of 90% platinum and 10% iridium.
4.
How many elements of the periodic table have only a single stable isotope?
- 0
- 15
- 26
Your answer:

Correct answer:

These so-called monoisotopic elements are beryllium, fluorine, sodium, aluminum, phosphorus, scandium, vanadium, manganese, cobalt, arsenic, rubidium, yttrium, niobium, rhodium, indium, iodine, cesium, lanthanum, praseodymium, europium, terbium, holmium, thulium, lutecium, rhenium, and gold.
5.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

Viking 1 carried two mass spectrometers, both equipped with double-focusing analyzers and electron ionization sources. The first spectrometer with a Mattauch-Herzog geometry was designed by Alfred Nier; it was intended to analyze the upper atmosphere of Mars. The second one with a Nier- Johnson geometry was part of the GC/MS apparatus designed by Klaus Biemann. It was used to analyze the regolith and the atmosphere at the landing site.
6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?
- Berlin, Germany
- Ostrava, Czechia
- Klosterneuburg, Austria
Your answer:

Correct answer:

Josef Mattauch was born in 1895 in the city of Mährisch Ostrau, in what is now the Czech Republic, then part of the Austrian-Hungarian Empire.
7.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?
- Burnaby Munson and Frank H. Field
- Michael Barber
- Hans-Dieter Beckey
Your answer:

Correct answer:

Chemical ionization was discovered in the laboratories of the Humble Oil and Refining Company in Baytown, TX. Munson and Field’s seminal paper on chemical ionization was published in 1966. [https://doi.org/10.1021/ja00964a001]
8.
Who built the first mass spectrometer in Czechia?
- Čermák, Hanuš, Jech, Cabicar
- Červinka, Dědek, Ferles
- Jára Cimrman
Your answer:

Correct answer:

The first mass spectrometer in the country was built in the Laboratory of Physical Chemistry of the Czechoslovak Academy of Sciences. Four young scientists, Vladimír Čermák, Vladimír Hanuš, Čestmír Jech and Josef Cabicar, took part in its construction. At the time of the post-war shortage, it was very difficult to find the necessary components; some parts originated from captured German military equipment. The mass spectrometer was of the Nier type with simple focusing and 60° magnetic field, pumped by a mercury diffusion pump. The device was completed after two years, in 1953. The construction of this instrument was an extraordinary achievement awarded a year later by the State Prize. [Z. Herman, Chem. Listy 104, 955, 2010]
9.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?
- 1868
- 1968
- 1989
Your answer:

Correct answer:

The solution of differential equations of this type came from the French mathematician Émile Léonard Mathieu (1835-1890), who studied the mechanical vibrations of the elliptical drumheads.
10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
What principle of positive ray detection was used in the first Thomson's parabola spectrographs?

2.
Which element has the largest number of stable isotopes?

3.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

4.
How many elements of the periodic table have only a single stable isotope?

5.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

8.
Who built the first mass spectrometer in Czechia?

9.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. What principle of positive ray detection was used in the first Thomson's parabola spectrographs?

2. Which element has the largest number of stable isotopes?

3. Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

4. How many elements of the periodic table have only a single stable isotope?

5. Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

6. Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

8. Who built the first mass spectrometer in Czechia?

9. The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

10. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museumof Mass Spectrometry

Our partners

1.
What principle of positive ray detection was used in the first Thomson's parabola spectrographs?

2.
Which element has the largest number of stable isotopes?

3.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

4.
How many elements of the periodic table have only a single stable isotope?

5.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

6.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

7.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

8.
Who built the first mass spectrometer in Czechia?

9.
The quadrupole mass filter has been known since the mid-1950s thanks to the work of Wolfgang Paul. The motion of ions in a quadrupole field can be described by solving second-order differential equations. When were these equations solved mathematically?

10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museum
of Mass Spectrometry