Mass Spectrometry Quiz

1.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?
- Francis William Aston
- Wolfgang Paul
- John Bennett Fenn
Your answer:

Correct answer:

Aston is a 44-kilometer lunar impact crater located along the northwestern limb of the Moon. The crater was named in honor of Francis W. Aston.
2.
The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

The first GC/MS experiments were carried out by Fred McLafferty and Roland Gohlke at Dow Chemical with Bill Wiley and Ian McLaren at Bendix Research Laboratories. They used a Bendix timeof- flight mass spectrometer, which had been commercially introduced in 1956. The instrument was fast enough to keep up with the changing output of the GC column.
3.
How long would be a paper needed for printing a profile mass spectrum measured in the m/z 0 1000 range at a resolution of 50,000 at m/z 500 if the peaks were to be 1 mm wide at their half maximum? Let us consider a constant width of all peaks.
- 1 m
- 10 m
- 100 m
Your answer:

Correct answer:

The resolution can be expressed as (m/z)/Δ(m/z), where Δ (m/z) is the peak width at 50 % of its maximum. For a resolution of 50,000 at m/z 500, the value of Δ(m/z) is 0.01. If the Δ(m/z) is to correspond to 1 mm, then the total width of the spectral record equals 1000/0.01 mm, which is 100,000 mm, which is 100 m.
4.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?
- Double-focusing mass spectrometer
- Time-of-flight mass spectrometer
- Quadrupole mass spectrometer
Your answer:

Correct answer:

Viking 1 carried two mass spectrometers, both equipped with double-focusing analyzers and electron ionization sources. The first spectrometer with a Mattauch-Herzog geometry was designed by Alfred Nier; it was intended to analyze the upper atmosphere of Mars. The second one with a Nier- Johnson geometry was part of the GC/MS apparatus designed by Klaus Biemann. It was used to analyze the regolith and the atmosphere at the landing site.
5.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?
- Burnaby Munson and Frank H. Field
- Michael Barber
- Hans-Dieter Beckey
Your answer:

Correct answer:

Chemical ionization was discovered in the laboratories of the Humble Oil and Refining Company in Baytown, TX. Munson and Field’s seminal paper on chemical ionization was published in 1966. [https://doi.org/10.1021/ja00964a001]
6.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?
- By confiscating almost year-round copper production from mines in the Belgian Congo
- By purchasing discarded copper stills from the Federal distillery in Port Melbourne
- By replacing copper with silver borrowed from the West Point Bullion Depository
Your answer:

Correct answer:

During the war, copper was preferably used for the production of brass shell casings and it was not available for the construction of calutrons. The designers came up with the idea of replacing copper with silver. They borrowed about 13,300 tons of silver from the West Point Bullion Depository in West Point, NY. After the war, the silver was returned to the Treasury with virtually no loss.
7.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).
8.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- Neither the trajectory nor the velocity of the particle changes
- The particle either accelerates or decelerates, depending on the field direction and the particle charge sign
Your answer:

Correct answer:

If a positive charge is moving in the same direction as the electric field vector the particle's velocity will increase. If it is moving in the opposite direction it will decelerate. If a negative charge is moving in the same direction as the electric field vector the particle will decelerate. If it is moving in the opposite direction it will accelerate.
9.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?
- Slovakia
- Czechia
- Poland
Your answer:

Correct answer:

The parents of John Zelený, Antonín Zelený and Josefa Pitková, came from Křídla, a small village near Žďár nad Sázavou in Austria-Hungary (now the Czech Republic).
10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

2.
The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?

3.
How long would be a paper needed for printing a profile mass spectrum measured in the m/z 0 1000 range at a resolution of 50,000 at m/z 500 if the peaks were to be 1 mm wide at their half maximum? Let us consider a constant width of all peaks.

4.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

5.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

6.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

7.
What is the electric charge of an ion with m/z = m?

8.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

9.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

2. The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?

3. How long would be a paper needed for printing a profile mass spectrum measured in the m/z 0 1000 range at a resolution of 50,000 at m/z 500 if the peaks were to be 1 mm wide at their half maximum? Let us consider a constant width of all peaks.

4. Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

5. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

6. Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

7. What is the electric charge of an ion with m/z = m?

8. What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

9. John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

10. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museumof Mass Spectrometry

Our partners

1.
Lunar craters are usually named after scientists and explorers. One of the craters on the Moon is named after a prominent scientist in the field of mass spectrometry. Who is named after?

2.
The first on-line coupling of gas chromatography to a mass spectrometer was reported in 1959. What type of spectrometer was used for this purpose?

3.
How long would be a paper needed for printing a profile mass spectrum measured in the m/z 0 1000 range at a resolution of 50,000 at m/z 500 if the peaks were to be 1 mm wide at their half maximum? Let us consider a constant width of all peaks.

4.
Which mass spectrometer was carried by the American spacecraft Viking 1 sent to the planet Mars in 1975?

5.
Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. Who discovered it?

6.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

7.
What is the electric charge of an ion with m/z = m?

8.
What is the trajectory of a charged particle moving parallel to a uniform electric field in a vacuum?

9.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

10.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

Czech Museum
of Mass Spectrometry