Mass Spectrometry Quiz

1.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?
- Slovakia
- Czechia
- Poland
Your answer:

Correct answer:

The parents of John Zelený, Antonín Zelený and Josefa Pitková, came from Křídla, a small village near Žďár nad Sázavou in Austria-Hungary (now the Czech Republic).
2.
What is the electric charge of an ion with m/z = m?
- 1 C
- 1.602 176 634 x 10^-19 C
- 1 eV
Your answer:

Correct answer:

The particle carries one elementary charge, the value of which is 1.602 176 634 × 10⁻¹⁹ C (exactly).
3.
What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?
- The particle follows a curved path and continues to follow this path until it forms a complete circle
- The particle follows a helical path
- The particle follows a straight line and accelerates
Your answer:

Correct answer:

The magnetic force is perpendicular to the velocity so that it does no work on the charged particle. The particle’s kinetic energy and speed thus remain constant. The direction of motion is affected but not the speed.
4.
How many elements of the periodic table have only a single stable isotope?
- 0
- 15
- 26
Your answer:

Correct answer:

These so-called monoisotopic elements are beryllium, fluorine, sodium, aluminum, phosphorus, scandium, vanadium, manganese, cobalt, arsenic, rubidium, yttrium, niobium, rhodium, indium, iodine, cesium, lanthanum, praseodymium, europium, terbium, holmium, thulium, lutecium, rhenium, and gold.
5.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?
- Berlin, Germany
- Ostrava, Czechia
- Klosterneuburg, Austria
Your answer:

Correct answer:

Josef Mattauch was born in 1895 in the city of Mährisch Ostrau, in what is now the Czech Republic, then part of the Austrian-Hungarian Empire.
6.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?
- 5
- 7
- 9
Your answer:

Correct answer:

A penta-quadrupole mass spectrometer contains three quadrupole filters and two rf-only quadrupole collision cells. It allows MS³ experiments. Extrel once offered such a spectrometer.
7.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:
- Gold
- Iridium
- Rhenium
Your answer:

Correct answer:

The International Prototype of the Kilogram was a cylinder with a height and diameter of 39 mm made of an alloy of 90% platinum and 10% iridium.
8.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?
- Electron ionization
- Fast atom bombardment
- Matrix-assisted laser desorption/ionization
Your answer:

Correct answer:

Mass spectrometry was used to sequence peptides for the first time in 1959 when K. Biemann described an innovative method based on the reduction of small peptides to polyamino alcohols with characteristic EI spectra. [https://doi.org/10.1021/ja01518a069]
9.
Who built the first mass spectrometer in Czechia?
- Čermák, Hanuš, Jech, Cabicar
- Červinka, Dědek, Ferles
- Jára Cimrman
Your answer:

Correct answer:

The first mass spectrometer in the country was built in the Laboratory of Physical Chemistry of the Czechoslovak Academy of Sciences. Four young scientists, Vladimír Čermák, Vladimír Hanuš, Čestmír Jech and Josef Cabicar, took part in its construction. At the time of the post-war shortage, it was very difficult to find the necessary components; some parts originated from captured German military equipment. The mass spectrometer was of the Nier type with simple focusing and 60° magnetic field, pumped by a mercury diffusion pump. The device was completed after two years, in 1953. The construction of this instrument was an extraordinary achievement awarded a year later by the State Prize. [Z. Herman, Chem. Listy 104, 955, 2010]
10.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?
- By confiscating almost year-round copper production from mines in the Belgian Congo
- By purchasing discarded copper stills from the Federal distillery in Port Melbourne
- By replacing copper with silver borrowed from the West Point Bullion Depository
Your answer:

Correct answer:

During the war, copper was preferably used for the production of brass shell casings and it was not available for the construction of calutrons. The designers came up with the idea of replacing copper with silver. They borrowed about 13,300 tons of silver from the West Point Bullion Depository in West Point, NY. After the war, the silver was returned to the Treasury with virtually no loss.

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

2.
What is the electric charge of an ion with m/z = m?

3.
What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?

4.
How many elements of the periodic table have only a single stable isotope?

5.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

6.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

7.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

8.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

9.
Who built the first mass spectrometer in Czechia?

10.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

Czech Museum
of Mass Spectrometry

Our partners

Mass Spectrometry Quiz

Mass Spectrometry Quiz

Thank you for taking our quiz!

1. John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

2. What is the electric charge of an ion with m/z = m?

3. What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?

4. How many elements of the periodic table have only a single stable isotope?

5. Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

6. What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

7. Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

8. What ionization technique was used for the first sequencing of peptides by mass spectrometry?

9. Who built the first mass spectrometer in Czechia?

10. Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

Czech Museumof Mass Spectrometry

Our partners

1.
John Zeleny was an American physicist whose work laid the theoretical foundations of electrospray ionization. He was born in 1872 into a family of immigrants from Europe. Where did his family come from?

2.
What is the electric charge of an ion with m/z = m?

3.
What is the trajectory of a charged particle moving perpendicularly to a uniform magnetic field in a vacuum?

4.
How many elements of the periodic table have only a single stable isotope?

5.
Josef Mattauch is known for the development of Mattauch-Herzog double-focusing mass spectrometer and his work on isotopes and atomic weights. His career is connected with the Kaiser Wilhelm Institute for Chemistry in Berlin. Do you know where he was born?

6.
What was the largest number of quadrupoles connected in series for tandem mass spectrometry in a commercial instrument?

7.
Until 2019, the kilogram unit was defined using an international prototype kept at the International Bureau of Weights and Measures in France. The International Prototype of the Kilogram was made of an alloy of platinum and one other metal. The metal was:

8.
What ionization technique was used for the first sequencing of peptides by mass spectrometry?

9.
Who built the first mass spectrometer in Czechia?

10.
Mass spectrometers known as calutrons were used for the industrial separation of uranium isotopes during the Manhattan Project. A large amount of copper was needed to make their magnetic coils. How was the highly-valued metal obtained during the war?

Czech Museum
of Mass Spectrometry